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Best CBD Vape Cartridge | Which Should I Buy?

As the CBD vaping industry continues to flourish, CBD users all over are looking for the best CBD oil cartridge on the market.

Cartridges are for vapers who already have a vaping device, as they simply click into place ready for use. Most CBD vapes are 510-thread, making them compatible with the majority of the CBD oil cartridges on the market. You can also get starter kits that contain both the device and the cartridge.

There are tons of CBD vape cartridges out there, so finding the best one can be tricky. We selected three of the top brands and compared their CBD vape cartridges to choose a final winner. But before we get into the full review, here’s a breakdown of what you need to know about CBD vape cartridges.

What Are CBD Vape Cartridges?

Simply put, a CBD vape cartridge is a small pod filled with CBD. It’s a cylindrical tank that contains a small amount of CBD e-liquid, and it clicks into a vape pen to provide a quick and easy vaping experience.

In case you were unaware, a CBD e-liquid is made from hemp-derived CBD and the typical base ingredients you would find in any other e-liquid. These usually include propylene glycol (PG), vegetable glycerin (VG), and medium-chain triglyceride (MCT) oils. Different brands will use different combinations of these ingredients, so it’s important to check the product descriptions and the label.

Many CBD lovers believe that vaporized CBD offers a much higher bioavailability than other methods.

CBD oil cartridges are disposable. Once the e-liquid in the tank runs out, you throw away the cartridge and replace it with a new one. However, this is more sustainable than a disposable vape pen, where you throw away the entire pen after use.

You can purchase CBD vape cartridges in a variety of strengths and flavors, so shop around until you find one that suits you. Of course, the most important thing is to ensure that it’s compatible with your vaporizer! 510-thread cartridges are the most common.

Vaping is a simple method of CBD consumption. All you need to do is use the vaporizer as per the instructions and inhale the vapor deeply. The CBD is absorbed via the respiratory system. Many CBD lovers believe that vaporized CBD offers a much higher bioavailability than other methods, making it more effective than ingested forms of CBD. Plus, many say that the CBD is faster-acting.

what are cbd vape cartridges?

Pros and Cons of Using CBD Vape Cartridges

  • Vaping is really quick and easy; all you need to do is inhale.
  • Advocates of vaping CBD say that it’s the fastest-acting method and provides the highest bioavailability.
  • Vape cartridges come in lots of delicious flavors.
  • There is no mess; you just click the cartridge into place and start vaping.
  • It’s relatively easy to monitor how much CBD you’re using.
  • Some research suggests that long-term vaping may pose health risks.
  • Vaping has a high initial cost, and cartridges can be expensive.


Short on time but eager to know our winner? Medix CBD pipped the other brands to the post in our search for the best CBD cartridge. It was a tough decision, but Medix CBD won based on safety, ease of use, and potency.

Advantages of Vaping CBD Compared to Smoking

Advocates of vaping have long suggested that it’s a safer alternative to smoking. Many in the cannabis community share this belief, insisting that vaping using a CBD cartridge is better for you than smoking high-CBD cannabis.

The reason for this belief is that vaporizing uses lower temperatures than smoking. When you smoke, you burn the plant matter and the paper that surrounds it, meaning that whatever you inhale is burned. Burned matter can contain carcinogens, which are dangerous to your long-term health. Plus, the high temperature isn’t great for your delicate respiratory system.

Vaping, meanwhile, uses much lower temperatures. As long as you use the right temperature setting, nothing is burned. The vapor may also be gentler on your airways. Furthermore, since the cannabinoids don’t reach their boiling point, they could be better preserved.

Another key advantage is the lack of smell. Any smoker will know that smoke clings to your clothes and the acrid smell is potent. Vapor, however, is less strong. The best CBD cartridges are also flavored, meaning that any vapor will be fruity and delicious rather than bitter and overpowering.

What Are the Different Types of CBD Vape Cartridge?

As with other CBD products, there are different types of CBD cartridges. You can get your hands on CBD isolate cartridges, full-spectrum cartridges, and even broad-spectrum options.

New to the world of CBD? Here’s a quick breakdown:

  • Full-Spectrum CBD: These products contain a full spectrum of cannabinoids and terpenes found in hemp. CBD products must contain less than 0.3% THC, but full-spectrum varieties have the highest amount out of all the varieties. Full-spectrum CBD usually has the strongest hemp flavor.
  • Broad-Spectrum CBD: When a brand says broad-spectrum, it usually means a full range of cannabinoids, but with no THC whatsoever.
  • CBD Isolate: This refers to a product that has all cannabinoids and terpenes removed, apart from CBD. It has the mildest flavor, and usually the highest concentration of CBD.

The type you choose is down to personal preference. Many CBD users believe full-spectrum CBD to be the most effective because the body can utilize numerous cannabinoids.

Cannabinoid content aside, you can also purchase refillable and disposable cartridges. Disposable ones are, by far, the most common, but some brands offer refillable options. In this case, you will need to purchase a battery, a cartridge, and an e-liquid. Refillable cartridges offer more versatility, but may also be more expensive.

Danger, High Voltage!

Many vape pens today offer adjustable temperature settings. Every time you change the temperature, you change the voltage setting on the device. Manufacturers work really hard to keep vape devices safe, but there are always things to keep in mind.

Some cartridges use a cotton wick. These cartridges are a little more old-school, and they can’t withstand high voltages. Cotton wick cartridges work best at a voltage of 3.6-3.8.

Ceramic cartridges, meanwhile, operate best in the low 4s. It’s more common to see ceramic options these days, but you should always read the packet just to be sure.

Going too high with your voltage can burn the liquid, resulting in bad flavor and an unpleasant experience.

Going too high with your voltage can burn the liquid, resulting in bad flavor and an unpleasant experience. There’s also little information on the health effects of inhaling burned e-liquid, so it’s something you had best avoid.

If you buy a CBD cartridge starter kit, you can often use the vape pen provided by the brand, which is a surefire way to know that they are compatible.

High CBD Vape Cartridges

When shopping online for high CBD cartridges, you will notice that they can contain varying amounts of cannabidiol. The key thing to look out for is the concentration of cannabidiol, i.e., the milligrams of CBD that the vape cart contains. Typically, CBD brands list the number as mg per serving, mg per hit, or drag, etc.

Bear in mind that some CBD retailers sell larger-sized cartridges that contain more servings rather than more mg of CBD. So, don’t let that fool you into thinking that you are getting more CBD per drag. In simple terms, the strongest CBD cartridge is the one that contains the highest mg amount of cannabidiol per serving.

CBD Cartridge Review

When looking for the best CBD vape cartridge on the market, there are some important factors to consider. Chief among these is the safety and quality of the vape products. Naturally, the transparency and reputation of the CBD brand are also crucially important.

As a consumer, it is always best to explore the brand’s website to see if they provide independent third-party lab reports. If so, you can see how much CBD each product contains. Lab reports give you greater peace of mind as you can be more confident that CBD vaping juice in the vape cart is safe. Companies that are open and transparent about where they source their CBD from also show the consumer that they are getting quality products when they shop with them.

Therefore, whether you’re looking for CBD oil, edibles, or CBD vape juice, it’s best to stick to reputable brands that provide lab reports. Remember, the best cannabis cartridge for you is not the cheapest one but the safest and highest quality one.

Best CBD Vape Cartridge

Unlike disposable vape pens that contain artificial flavorings in a pre-filled vape cart, a premium quality vaping device allows you to choose a CBD vape cartridge that comes in a variety of flavors.

As mentioned, when a disposable vape pen is empty, you simply bin it. Similarly, once the CBD vaping juice is gone, you discard the vape cartridge and replace it with a new vape cart of your choice.

You’ll find that the best CBD cartridges indeed do come from the market leaders in the CBD industry. It’s no coincidence that the brands with a high-quality CBD vape cartridge best the other brands in the market. They also have some of the highest quality ingredients available.

In the next section, we’ll identify the brands that we believe sell the best CBD vape cartridges and the reasons why we chose them.

Which Brand Sells the Best CBD Vape Cartridge?

In our ranking of the best CBD cartridges, we judged three brands according to: Flavor, safety, ease of use, potency, and price. It was even difficult to pick the three top brands, but in the end, we settled on:

  • Just CBD
  • Cheef Botanicals
  • Medix CBD

which brand sells the best cbd vape cartridge?

WayofLeaf works hard to earn your trust and provide well-researched and accurate information. Here you can read about How we select our products

Best Tasting CBD Vape Cartridge

Selecting the best CBD cartridge in terms of flavor is difficult because it depends on personal preference. The brands on our list have a combination of cannabis flavored cartridges and other, more typical vaping flavors.

Medix CBD has three options, all of which are flavored with terpenes. In other words, they taste very much like hemp and cannabis. While the taste is refreshing and mild, it’s also not to everyone’s taste.

Cheef Botanicals and Just CBD both sell a mixture of the two flavor types. Cheef Botanicals have nine flavors on offer, while Just CBD offers twelve. In our humble opinion, the Just CBD range is better, not only because it’s larger but also because there’s more variety.

Just CBD stocks a few different cannabis strain flavors. There are also fruits like Strawberry and dessert flavors like Vanilla Custard Cream. Please note that these cartridges may contain artificial flavorings, but all the ingredients are food-grade. Regardless, these were the most delicious cartridges we tried.


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Best for Safety

When shopping for CBD products, it’s vital to check the ingredients and always buy from a brand with third-party lab reports. The main culprit for health issues in vape products is PEG and none of the products we’re reviewing contain this ingredient to our knowledge. Little is known about the long-term effects of propylene glycol (PG), but there is potential for risk here, too.

Cheef Botanicals provides lab reports for the CBD cartridge. The reports confirm that the cannabinoids listed on the packet are correct. However, the brand claims not to use PG, VG, MCT, or PEG; we’re not sure what the base of the e-liquid actually is!

Just CBD uses a blend of USP propylene glycol and VG, which is what most companies use. There are lab reports available on the website, and again these confirm the cannabinoid content of the products.

Out of the three, Medix CBD is the only brand that tests for heavy metals and mycotoxins. By the way, both of these compounds were not detected in the vape cartridges. However, Medix CBD doesn’t specify the base liquids used in its cartridges.

In the end, we think Medix CBD wins for safety, simply because you can search lab reports for specific batch numbers. That way, you can feel safe with every purchase.



Best for Ease of Use

All of the brands made cartridges that are pretty easy to use. The Cheef Botanicals cartridges are compatible with any 510-threaded device, so all you need to do is click it into your vape pen and get puffing.

Similarly, the Just CBD cartridge works with any 510-thread battery that does 450mAh and above. It’s a slightly narrower usage but still works with most devices.

The Medix CBD cartridges actually come with a disposable battery attached, which means you can vape them straight out of the box with no other device necessary! As a result, we think this is the easiest cartridge to use because it requires no assembly.



Best CBD Concentration

All three brands offer different concentrations of CBD. Cheef Botanicals offers two potency options: 200mg and 400mg. All of the Just CBD options contain 200mg. Medix CBD offers the highest amount of CBD, with a 500mg option alongside its 250mg offering.

However, you should note that the 500mg cartridge is simply larger than its 250mg counterpart. As a result, the concentration of CBD is the same. You get 2.5mg per puff with both cartridges.



Best Budget Pick

To choose the best pen on a budget, you could be looking for the cheapest CBD cartridge or the one that gives you the most bang for your buck. The cheapest overall is the Just CBD cartridges, costing just $15.99. The Signature Cartridges (based on cannabis strains) are $22.99, which is also cheaper than the other brands.

Here is the price per milligram of each brand’s most expensive option:

  • Cheef Botanicals (400mg): $0.09 per milligram
  • Just CBD (200mg Signature Cartridge): $0.11 per milligram
  • Medix CBD (500mg): $0.12 per milligram

So, while Cheef Botanicals offers the best value for money when opting for a more potent cartridge, Just CBD offers the cheapest cartridge overall.


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Medix CBD is our top brand for vape cartridges based mainly on strength, ease of use, and safety. The lab reports are second to none and we love the fact that the three varieties are dedicated to providing different effects.

Nevertheless, Medix CBD only provides terpene-flavored CBD cartridges. If you’re looking for tastier flavors, then Just CBD would be our second choice.

Make sure you visit the Medix CBD website to explore the vaping range.


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