Chem’s Sister Strain Review + Info

Chem’s Sister Strain Review + Info

Chem's Sister is a phenotype of the famous OG strain Chemdawg. This sativa-dominant hybrid induces euphoria and uplifts users’ mood. It is a popular choice among cannabis consumers who want a long-lasting buzz followed by gentle relaxation.

Dominant Terpene:
Calming, Euphoria, Happy, Relaxation, Uplifting
Common Usage
AnxietyChronic painDepressionFatigueLack of appetiteNauseaStress
Growing Info
Clone-only strain. Chem’s Sister flowers between 10-12 weeks indoors and outside harvesting is around mid October to early November.

It is surprising how much variation there is in the world of weed. The individuality of every strain is down to various factors, including cannabinoid content, terpenes, flavonoids, and more.

Reading strain reviews before taking a trip to the dispensary can be helpful, especially if you’re a medical user. If you’re in the market for an uplifting sativa strain, you might want to check out Chem’s Sister. So, please sit back and relax as we give you the lowdown on this mood-enhancing strain.

What Is Chem’s Sister?

You may already be familiar with the Chemdawg strain. The ‘chem’ part of the name comes from its distinct diesel and chemical aroma.

Chemdawg is a popular hybrid strain, renowned for relaxing and sedative effects. What if you want a strain that tastes like Chemdawg but provides less sedating effects?

Enter Chem’s Sister. This strain is a phenotype of Chemdawg, meaning they share similar traits but have a few differences.

Chem’s Sister weed is a sativa-dominant hybrid that leaves users feeling more uplifted, creative, and focused after consuming this strain.

As might be expected from a relative of Chemdawg, it provides a diesel-like and skunky smoke. For the more traditional marijuana users, this flavor is considered a delicacy. Plus, there are some pleasant undertones of citrus that make Chem’s Sister a slightly fresher smoke.

Chem’s Sister first hit the market in 1996 and has been growing in popularity ever since. It also goes by names such as Chem Sis and Chemdawg A.

In 2016, this strain came third in the Best Medical Hybrid category at the High Times Cannabis Cup. High Times also mentioned this strain in the list of 25 Greatest Strains of All Time.

Some of Chem’s Sister’s popularity comes down to the uplifting, euphoric effects. However, it would be remiss if we didn’t mention some notable attributes of this plant.


Chem’s Sister’s aroma bears a strong resemblance to Chemdawg’s as it has a similar chemically and fuel-like odor. Think of a gas station, and you’re pretty much there. This scent only becomes stronger as you break the buds apart in the grinder. Be prepared for this overpowering, skunky aroma to fill the room.

There are also some detectable citrusy notes. These lemony undertones creep through in the scent, adding a more pleasant side to the sour diesel.

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You might expect the diesel smell to carry over into the taste. While this is in part true, Chem’s Sister tastes a bit sweeter. Among the bitter chemical taste, there is the presence of sandalwood and citrus.

Some users can also detect a crisp pine taste. Upon exhaling, however, the diesel flavor becomes more apparent.


Chem Sis’ mint green buds appear quite frosty due to a generous coating of trichomes. These tend to darken with age and are very sticky to the touch.

Chem’s Sister Grow Info

Unfortunately, Chem’s Sister is a clone-only strain, and seeds are not available online. It is a moderately difficult strain to grow, so it’s unsuitable for novices.

Chem’s Sister is best-suited to a Mediterranean-type climate with warm temperatures and lots of sunlight. If you don’t live in this kind of environment, you may want to opt for indoor cultivation. For the best possible terpene profile, use soil as the growing medium.


Indoor growing provides another advantage: You can control the humidity level. This is essential because Chem’s Sister plants are susceptible to mold and mildew. Therefore, it’s crucial to invest in a ventilation system that sucks excess moisture out of the room.

Indoors, you are looking at a flowering period of between 10 and 12 weeks. Outside, it can flower anywhere between the third week of October and the first week of November.

Yields tend to be higher from an outdoor grow – at least 16 ounces per square meter on average. Indoors, Chem’s Sister produces around 12-16 ounces per square meter. However, if you use the Screen of Green (SCROG) method, you may increase trichome production and yield.

THC Content – Highest Test

Chem’s Sister cannabis is exceptionally potent. On average, you can expect 22.5% THC. However, some samples soar as high as 28%.

CBD Content – Highest Test

Chem’s Sister does not contain CBD.

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Medical Benefits of Chem’s Sister

Given Chem Sis’s high THC content, some users may find relief from various painful conditions. For example, Chem’s Sister may help to alleviate muscle aches, joint pain, and headaches.

As Chem’s Sister has an uplifting effect on its users, it may offer temporary relief from mood disorders like depression. Some users say that Chem’s Sister can help to relieve nausea and increase appetite, too.

Potential Side Effects of Chem’s Sister

Many Chem Sis users will experience dry mouth and dry eyes. Other possible adverse reactions include heightened anxiety and paranoia. As Chem’s Sister contains a high THC content, novices should avoid this strain.

Final Thoughts on Chem’s Sister

If you love Chemdawg, then you’ll likely enjoy its phenotype, Chem’s Sister. Both strains pack a similarly potent THC level and provide a euphoric and uplifting high. One difference between the two related strains is that Chem Sis is not as sedating as Chemdawg.

Please note Chem Sis’s high THC content, which can reach a staggering 28%.

Naturally, novices should avoid this strain. Experienced users would be wise not to over-consume to prevent any unpleasant adverse reactions.

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