According to the CDC, about 37% of Americans are living with elevated cholesterol; a condition that potentially doubles the risk of developing cardiovascular disease. Worryingly, only 55% of adults who need medicine to treat this issue are using it. The problem with detecting high cholesterol is that it’s symptomless; you could have the condition without even realizing it.
If a doctor diagnoses you with high cholesterol, it’s likely they will recommend a medication known as a statin. Statins can help lower the risk of things like heart attack and stroke by over 30%.
However, there are a list of adverse side effects that come along with most prescription statins. For example, patients with high cholesterol that take statins may experience migraines, trouble sleeping, drowsiness, dizziness, nausea, and gastrointestinal issues, just to name a few. Statins can also increase the likelihood of developing neuropathy, loss of memory, and even type-2 diabetes.
CBD oil for lowering cholesterol; is there any merit to the discussion?
Given the popularity of CBD oil in recent years, the discussion of using CBD oil to lower cholesterol has been brought up. But is there any clinical proof of CBD having an effect on cholesterol levels?
In this article, we look at what cholesterol is and why you’re likely to have high cholesterol. We’ll also examine various problems associated with statins, and discuss relevant scientific research relating to cannabis, CBD, and cholesterol levels.
What is Cholesterol?
Cholesterol is a lipid found in your body’s cells. Though it generally has a negative connotation given its link to heart disease, cholesterol is actually essential and serves many important functions. It influences the creation of hormones, the synthesis of vitamin D, and helps to digest food correctly.
Cholesterol categorizes into two types: Low-Density Lipoproteins (LDL, aka ‘bad’ cholesterol), and High-Density Lipoproteins (HDL, aka ‘good’ cholesterol).
HDL helps remove LDL deposits and limits the buildup of plaque that leads to things like heart attack and stroke. If LDL levels are too high, plaque accumulation inside blood vessels can cause arteries to harden and become narrower. Plaque buildup can cause arteries to become fully blocked. A blocked artery prevents blood from reaching vital organs and tissues. The result is a heart attack or stroke.
What Causes High Cholesterol?
Typically, your cholesterol level increases with age. There are a number of lifestyle choices that contribute to increased LDL cholesterol levels, such as smoking, being overweight, and eating too many saturated fats. Dietary culprits that typically lead to high cholesterol are dairy items, processed foods, and fatty red meats. A lack of physical activity can also negatively impact cholesterol levels. This is why many health experts suggest a minimum of 20 minutes of physical activity a day.
The Problem with Statins
The first thing any person with high cholesterol levels might want to do is take a long, hard look at their lifestyle. They may want to incorporate fish, lean meats, low-fat products, fruit, vegetables, and whole grains into their diet. As for smokers, most any health professional would recommend quitting in order to lower excessive cholesterol levels.
In terms of medication for lowering cholesterol, it is common for physicians to prescribe statins. Statins inhibit an enzyme that the liver needs to produce LDL cholesterol. They also slightly increase HDL levels, which can move ‘bad’ cholesterol from the arteries to the liver.
Millions of Americans are currently using statins, and health experts suggest that millions more need to be using them. For example, the American College of Cardiology issued a set of recommendations for statins suggesting over 26 million Americans should be using them.
There’s a problem with these recommendations…
According to these numbers, at least one-third of people aged 40-75 with no history of cardiovascular problems should be on statin medication. Since statistics on the effectiveness of statins vary, however, Dr. Rita Redberg of the University of California in San Francisco suggests using cholesterol calculating tools – like the Framingham Calculator – to estimate personal cardiovascular risk.
Also, a realistic concern with statin use is the range of adverse side effects that they produce. Statins can cause things like liver damage and rhabdomyolysis – a condition that damages muscle cells. Further concerns include an increased risk of type 2 diabetes, increased blood sugar, and memory problems. That’s a lot of risk for a drug that may not help you in the long run.
Is CBD a Better Alternative for Lowering Cholesterol?
To put it bluntly, there is no clinical evidence on the use of CBD to lower cholesterol levels. No one should suggest or recommend that CBD can function in place of statins, or even in place of a lifestyle change.
That said, one study does discuss a potential relationship between cannabidiol use and “cholesterol metabolism-related genes.” The study, which appears in a 2011 edition of Cellular and Molecular Neurobiology, suggests that “CBD treatment modulates cholesterol homeostasis in microglial cells.”
Does this mean you can use CBD to help lower your cholesterol?
Not quite. While the findings of this particular study are intriguing, the results have no clinical bearing on the use of CBD for cholesterol level management.
A separate 2017 study in Cannabis and Cannabinoid Research also discusses the effect of CBD use on cholesterol. The study claims that CBD “increased cholesterol levels in WT [wild-type] mice, but not in CBD-treated transgenic [laboratory-bred] mice.” Researchers state that the lack of effect on cholesterol in the transgenic mice was likely due to “already-elevated cholesterol [levels] in the transgenic mice.”
Interestingly, later in the study researchers discuss the potential benefits of cannabidiol on hyperglycemia. In obese mice, it was observed that a four-week CBD treatment of 3 mg per kg of body weight “increased HDL-C concentration by 55% and reduced total cholesterol levels by more than 25%.”
Again, although this research is very interesting, it has no bearing on the practical use of CBD oil for lowering cholesterol levels. While there may indeed be a physiological relationship between the two, more research is needed.
Final Thoughts on CBD Oil for Reducing LDL Cholesterol
All in all, there is no explicit clinical evidence that CBD oil (or any other CBD product) can help reduce cholesterol levels. Many full-spectrum CBD oils contain healthy omega acids, which may help reduce the likelihood of cardiovascular disease. Again, however, this does not denote that CBD has any specific relationship with blood cholesterol levels.
Remember, however, that research into CBD is still very much in its infancy. There may be additional physiological properties of CBD that relate to cardiovascular health, but for now, little is known on the topic. As research improves, we are likely to witness some exciting discoveries in the future.