5 Best Cannabis Strains for an Imbalance in Hormones

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There are thousands of scientifically researched studies available on the health benefits of marijuana. You can also read countless articles, reviews, and testimonials that back up these claims. Some studies suggest a specific type of strain is best to treat depression, while another is perfect for digestive problems. We see so much information relating to a massive range of health issues and how marijuana is potentially the answer!

Without real reasoning behind it, the medical marijuana industry has evolved where it focuses more on male-orientated problems. Indeed, the pharmaceutical industry, as a whole, is accused of gender bias! As a result, there is less information about the potential health benefits marijuana could have for female-specific issues. A prime example is how cannabis impacts female hormones.

Hormonal imbalance indeed affects both men and women. However, it primarily impacts females and can have a deleterious impact on their daily lives if left untreated.

The majority of women endure a monthly period, which comes with a host of unpleasant symptoms. The worst is arguably premenstrual syndrome (PMS). It can begin as early as two weeks before a woman is due to have her period. PMS involves a wide range of physical and emotional side effects. Even though PMS isn’t the only thing behind female hormonal imbalance, it causes many of the issues.

In this article, we discuss how different marijuana strains help women worldwide deal with hormonal imbalances. We also look at five of the best options.

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What Is a Hormonal Imbalance?

A shift in our hormones is not uncommon or a cause for concern. Something as insignificant as a bad night’s sleep can affect your hormone levels the day after! However, hormonal imbalance is more serious. It could have a long list of side effects that impact a woman’s quality of life dramatically.

Symptoms include:

  • Persistent weight gain
  • Fatigue
  • Digestion problems
  • Poor quality of sleep
  • Low libido
  • Anxiety
  • Depression
  • Loss of muscle mass

These imbalances occur for several reasons, including poor diet, unhealthy lifestyle, diabetes, high stress, and so many more.

You can relieve some issues by having a healthier diet and regularly exercising. However, the majority of women have PMS monthly for a considerable portion of their lives. It is this that results in most of the issues within the hormone system.

How Can Having a Hormone Imbalance Affect Your Life?

Adverse effects include lack of sleep, lethargy, and anxiousness. These can lead to more severe issues such as insomnia and depression. PMS alone brings with it stomach cramps, backache, tender breasts, headache, and nausea. Imagine having several of these symptoms at once for 2-3 weeks each month!

There are, however, more serious long-term side effects of having a hormone imbalance. Potential problems include infertility, endometriosis, hair loss, and memory loss.

Hormones work in a large variety of bodily processes. Therefore, if the level of hormones decreases, they can’t do their job within the body.

Traditional Treatments for Hormonal Imbalance

There are several treatment options, including HRT or Hormone Replacement Therapy. HRT is usually for women dealing with the symptoms of menopause. It works to replace some of the lower level hormones in the body to regulate hormone levels.

There are also herbal remedies that bring your body back in balance and eradicate some of the symptoms at the same time. Of course, there isn’t much scientific evidence to support such assertions.

The standard solution is to treat the symptoms rather than the imbalance itself. Therefore, a woman with anxiety and depression may receive therapy and a long-term course of antidepressant medication. Alternatively, they get strong pain relief medication to take during the menstrual period. This method only deals with the symptoms and does nothing to tackle the underlying cause.

We don’t necessarily need to use dozens of different drugs. We can work towards a healthier lifestyle, reduce life stresses where possible and eat a more nutritional and balanced diet. However, it is unlikely that these things will make a significant impact during that ‘time of the month.’

Is Marijuana for Hormone Imbalances Different?

Cannabis potentially regulates various body functions ranging from mood to pain management. It achieves this by interacting with the body’s endocannabinoid system (ECS).

A study by Harclerode, published in NIDA Research Monograph in 1984, was one of the first to look into weed and hormones. He found that THC seemingly alters neurotransmitters located in, or linked to, the hypothalamus.

The hypothalamus is the part of the brain that connects the nervous system with the endocrine system, which produces our hormones. There is research on how using marijuana weekly can reduce the sperm count of men. THC blocks the release of GnRH. This is a hormone that results in the release of other hormones. This process possibly reduces male testosterone production.

There is less research on cannabis and female hormones. The evidence we have to date suggests that females absorb weed differently depending on their estrogen levels.

A study by Wakley et al., published in Pharmacology, Biochemistry, and Behavior in June 2015, made an exciting discovery. It found that female rats are around 30% more sensitive to THC than their male counterparts.

Professor Rebecca Craft was a co-author of the study. She said that there is a definite spike in THC sensitivity when females are ovulating. Across ten days, the female rats became more tolerant of the intoxicating compound than males. This indicates that women are more likely to build up cannabis tolerance than males.

Could marijuana help reduce the pain of PMS and related hormonal imbalances? We need clinical studies to find out more.

Let’s Take a Look at the Top 5 Marijuana Strains for Hormonal Imbalance!

1. Harlequin (The Energizer CBD Marijuana Strain)

Harlequin is a relaxing strain, and can ease some of the stresses that come with a hormone imbalance! It is an eclectic mix of Swiss Sativa, Nepali and Thai landraces, and Colombian Gold. It has a potential CBD to THC ratio of 5:2. Its THC content ranges from 7% to 15%. Meanwhile, its CBD level is between 10% and 15%.


Harlequin is a sativa-dominant hybrid. The high CBD content means you shouldn’t feel intoxicated. However, users report feeling chilled out, though they still retain a semblance of focus. You should feel uplifted when you use Harlequin, and it has a reputation as a powerful painkiller. This is ideal if you are feeling the agony of PMS.

2. Sweet and Sour Widow (Perfect for Improving Sleep)

Jamie from Resin Seeds teamed up with Mr. Shantibaba from Mr. Nice Seeds in 2009 to create Cannatonic. However, not many people know that they also created Sweet and Sour Widow. It is a CBD-enriched version of White Widow. This strain is an indica-dominant hybrid with an even CBD to THC ratio. It tends to include 5-11% of each.


Sweet and Sour Widow is the go-to cannabis strain if you are suffering from insomnia or reduced appetite. As it happens, both are common symptoms of hormone imbalance. This cannabis strain is the perfect strain for evening and night time use. If you have issues getting to sleep due to hormonal imbalance, give Sweet and Sour Widow a try.

3. Dutch Treat (The Social Marijuana Strain)

Dutch Treat is an indica-dominant hybrid with a THC content ranging from 18% to 25%. Its roots are unknown, though it possibly originated in Vancouver, Canada. It gets its name because of its popularity in Amsterdam. However, this strain quickly gained fame across Europe and North America.


It offers a higher level of THC than most of the ones we have mentioned so far. However, it provides a mild high that is perfect for social events. This is especially the case if you are looking to take your mind off those hormonal imbalances. Dutch Treat could offer relief from issues such as nausea, headache, chronic pain, and even insomnia. You are better off consuming this strain at night or when socializing to get the most out of it.

4. Jillybean (The Positive Mindset Strain)

Jillybean is a gorgeous-tasting, sativa-dominant hybrid developed by TGA Subcool Seeds. It gets the name due to its candy-like taste. It is a cross of Orange Velvet and Space Queen, with a THC content of 15-18%, and up to 1% CBD. Users adore the flavor combination of mango and citrus, a mouth-watering strain!


Jillybean delivers a mild and relaxing body high while potentially combating symptoms of pain, aches, cramps, stress, anxiety, and depression. You should use it during the day as it works to maintain a positive mindset and promotes productivity. The uplifting body high lasts for hours and possibly keeps the pain of hormonal imbalance at bay.

5. Obama Kush (Feel Relaxed and Totally Chilled Out)

As the name suggests, this indica-dominant hybrid strain gets its name from former POTUS, Barack Obama. It has a well-balanced and uplifting effect, so we guess that the breeders are fans of the ex-president! Superior Genetics created Obama Kush in a Michigan Lab. It is a cross of Afghani and OG Kush, with a THC content of 14-21%. Its CBD level is minimal at 0.2%.


Obama Kush could make the user feel relaxed. It is an option for calming the stress levels that come with hormonal imbalances. It also provides possible pain relief and could help with both breast tenderness and cramping. You should use this strain in the evenings before bed, or if you plan to stay indoors.

Final Thoughts on Marijuana Strains for Hormonal Imbalance

Marijuana potentially has a massive positive impact on women suffering from hormone imbalance. It provides possible relief from those nasty symptoms that come with menstruating 12 times a year!

The strains on offer are limitless, depending on what you seek.  However, the five we have listed contain a nice range of high THC and high CBD options.

Unfortunately, there is a lack of clinical evidence to support cannabis use for hormonal imbalance. However, the research to date suggests a benefit to both male and female hormone systems. There is plenty of anecdotal evidence from women who hail cannabis as a PMS symptom buster.

Try Legal THCA Flower

Want to experience the qualities of THC-A flower? The amazing brand Premium Jane just launched their new line, including strains like OG Kush, Purple Cream, and Blue Dream Pie. Averaging 23% THC-A, there’s so much to love with these flowers. Try them today to get 20% off using WayofLeaf’s exclusive coupon code: THCAWOL

Visit Official Site
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